Single-cell Omics
Functional Genomics
Cancer Immunology
Innovative researcher advancing precision medicine through computational biology
I'm an innovative researcher with expertise in Next-Generation Sequencing and cancer immunology, with a strong track record of developing novel methodologies and leading high-impact projects. Currently pursuing my Master's in Bioinformatics and Systems Biology at New York University while conducting cutting-edge research at the New York Genome Center.
My research focuses on understanding tumor microenvironments, developing novel therapeutic approaches, and advancing precision medicine through computational biology and single-cell analysis. I'm adept at developing analytical pipelines and collaborating with cross-functional teams.
Contributing to the advancement of scientific knowledge
Showcasing innovative research and development
A lightweight Python package for single-cell perturbational profiling and drug discovery workflows. Features modern Python project structure, device auto-selection (CUDA/MPS/CPU), and ML utilities for CMap analysis.
View ProjectAI-powered hemocytometer analysis mobile app built with React Native and TensorFlow. Automated cell counting, viability assessment, and professional PDF reporting for laboratory research.
View ProjectA comprehensive, production-ready single-cell immune atlas for tumor-infiltrating lymphocytes (TILs). Multi-dataset integration with advanced QC, batch correction, and immune cell annotation.
View ProjectSingle-cell RNA-seq analysis of High-Grade Serous Ovarian Cancer focusing on platinum-based chemotherapy resistance mechanisms.
View ProjectJourney through cutting-edge research and innovation
Investigate synthetic genes in various cell types and diseases
Played a key role in developing Quantum Barcoding technology single-cell RNA assay using combinatorial indexing.
Delivered scRNA-seq analysis of high-grade serous ovarian cancer, delivering key insights into platinum-based chemotherapy resistance (1st author publication).
Led a project investigating tumor microenvironment changes in pancreatic ductal adenocarcinoma, uncovering significant changes in tumor-infiltrating lymphocytes and macrophage polarization upon SUMOylation inhibition (1st author publication).
Tools and technologies driving innovation
September 2024 - May 2025 | New York, NY
General Biology | Political Science - Data Analytics
January 2019 - July 2021 | La Jolla, CA
Interested in collaboration, research opportunities, or just want to chat about bioinformatics and cancer research? I'm always open to discussing innovative projects and potential partnerships.
james.hyojae.lee@gmail.com
(858) 210-1206
Professional Profile
@JamesHyojaeLee
Code Portfolio
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📍 New York, NY 10013
"Advancing precision medicine through computational biology and single-cell genomics"